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[Slika]

dr Sanja R. Grgurić Šipka

redovni profesor
Hemijski fakultet, Studentski trg 12-16, Beograd
Katedra za opštu i neorgansku hemiju

Telefon:   011-3336736 (u laboratoriji 525), 011-3336742 (u kabinetu 534)

Telefon (lokalni):   736 (u laboratoriji 525), 742 (u kabinetu 534)

Kabinet:   534

Laboratorija:   525

E-mail:   sanjag AT chem · bg · ac · rs

Lični podaci

Rodjena 28.08.1971. u Beogradu. Udata. Dvoje dece.

Obrazovanje i usavršavanja

1994: Osnovne studije - Hemijske nauke / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1998: Magistratura - Hemijske nauke / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2003: Doktorat - Hemijske nauke / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

Kretanje u službi

1995: Stručni saradnik pripravnik / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1997: Asistent pripravnik / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1999: Asistent / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2004-2010: Docent / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2010: Vanredni profesor / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2015-2016: Redovni profesor / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

Oblasti naučnog interesovanja

Koordinaciona hemija, bioneorganska hemija

Nagrade i priznanja

2005: Stipendija Austrijskog naucnog fonda, Lisa Meitner

Ostale aktivnosti

Član Srpskog hemijskog društva od 1994.

Šef Katedre za opštu i neorgansku hemiju od 8. 3. 2011. do 20. 1. 2016.

Angažman u nastavi

Projekti

Brojevi za identifikaciju autora

Izabrane reference

Knjige i revijalni radovi / Books and reviews:

  1. Sabo, T. J.; Grgurić-Šipka, S.R.; Trifunović, S.R. Transition metal complexes with edda-type ligands. Synth. React. Inorg. Met.-org. Chem., (2002) 32 1661-1717.
  2. Gligorijević,N.; Arandjelović,S.; Jovanović, K.; Grgurić-Šipka, S.; Radulović, S.: The development of Ru(II)-p-Cymene derivativesd as Anti-Cancer Agents, in Ruthenium Chemistry (2017), CRC Press, Taylor and Francis. 
  3. M.Gruden-Pavlović, S.Grgurić-Šipka, S.Grubišić, S.R.Niketić, Praktikum iz opšte hemije, Hemijski fakultet, Beograd, 2008.
  4. S. Grgurić-Šipka, Hemija bioelemenata, Hemijski fakultet, Beograd, 2014.

Izabrani radovi / Selected papers:

  1. Pavlović, M.; Nikolić, S.;  Gligorijević, N.; Dojčinović, B.; Aranđelović, S.; Grgurić-Šipka, S.; Radulović, S.: New organoruthenium compounds with pyrido[2',3':5,6]pyrazino[2,3-f][1,10]phenanthroline: synthesis, characterization, cytotoxicity and investigation of mechanism of action, J. Biol. Inorg. Chem., 24 (2019)  297-310. 
  2. Pantić, D.N.; Mihajlović-Lalić, Lj:E; Aranđelović, S.; Radulović, S.; Grgurić-Šipka, S.: Synthesis, characterization and cytotoxic activity of organoruthenium(II)-halido complexes with 4-chloro-1H-benzimidazole-2-carboxylic acid, J. Coord. Chem., 72 (2019) 908-919.
  3. Nikolić, S.; Grgurić-Šipka, S.; Djordjević, I.S.; Dahmani, R.; Dekanski, D.; Vidičević, S.; Tošić, J.; Mitić, D.; Grubišić, S.: Half-Sandwich (Arene) Ruthenium(II) complexes: Synthesis, Spectroscopic Studies, Biological Properties and Molecular Modeling, J. Coord. Chem., 72 (2019) 148-163.
  4. Korać, J.; Stanković, D.; Stanić, M.; Bajuk-Bogdanović, D.; Žižić, M.; Bogdanović Pristov J.; Grgurić-Šipka, S.; Popović-Bijelić, A.; Spasojević, I.: Coordinate and redox interactions of adrenaline with ferric and ferrous iron at pH 7.4, Sci. Rep., 8 (2018) 3530
  5. Poljarević, J.; Tamas Gal, G.; May, N.V.; Spengler, G.; Domotor, O.; Savić, A.R.; Grgurić-Šipka, S.; Enyedy, E.A.: Comparative solution equilibrium and structural studies of half-sandwich ruthenium(II)(n6-toluene) complexes of picolinate derivatives, J. Inorg. Biochem., 181 (2018) 74-85. 
  6. Tadić, A.; Poljarević, J.; Krstić, M.; Kajzerberger, M.; Aranđelović, S.; Radulović,S.; Kakoulidou, C.; Papadopoulos, A.N., Psomas, G.; Grgurić-Šipka, S.: Ruthenium arene complexes with NSAIDs: Synthesis, characterization and bioactivity, New. J. Chem., 42 (2018) 3001-3019.
  7. Nikolić, S.; Ćirić, I.; Roller, A.; Lukes, V.; Arion, V.B.; Grgurić-Šipka, S: Conversion of hydrazides into N,N'-diacylhydrazines in the presence of ruthenium(II)-arene complexes, New J. Chem., 41, 2017, 6857-6865.
  8. Misirlić-Denčić, S.; Poljarević, J.; Isaković, A.M.; Marković, I.; Sabo, T.J.; Grgurić-Šipka, S.: Antileukemic action of novel Pt(II) halogenido complexes: Comparison of the representative novel Pt(II) complex with the corresponding Pt(IV) complex, Chem. Biol. Drug. Des., 90, 2017, 262-271. 
  9. Pantić, D.N.; Aranđelović, S.; Radulović, S.; Roller, A.; Arion, V.B.; Grgurić-Šipka, S: Synthesis, characterisation and cytotoxic activity of organoruthenium(II)-halido complexes with 1H-benzimidazole-2-carboxylic acid, J. Organomet. Chem., 819, 2016, 61-68. 
  10. Nikolić, S.; Rangasamy, L.; Gligorijević, N.; Aranđelović, S.; Radulović, s.; Gasser, G.; Grgurić-Šipka, S:Synthesis, characterization and biological evaluation of novel ruthenium(II)-arene complexes containing intercalating ligands, J. Inorg. Biochem., 156, 2016, 156-165. 
  11. Nikolić, S.; Opsenica, D.M.; Filipović, V.; Dojčinovič, B.; Aranđelović, S.; Radulović, S.; Grgurić-Šipka, S.: Strong in vitro Cytotoxic Potential of New Ruthenium-Cymene Complexes, Organometallics, 34, 2015, 3464-3473.
  12. Marzo, T.; Savić, A.; Massai, L.; Michelucci, E.; Sabo, T.J.; Grgurić-Šipka, S.; Messori, L.: Reactions of Cytotoxic Metallodrugs with Lysozime in Pure DMSO explored through Uv-Vis Absorption Spectroscopy and ESI MS, Bioemetals, 28, 2015, 425-430.
  13. Savić, A.; Filipović, L; Aranđelović, S.; Dojčinovič, B.; Radulović, S.; Sabo, T.J.; Grgurić-Šipka, S: Synthesis, characterization and cytotoxc activity of novel Pt(II) iododo complexes, Eur. J. Med. Chem. 82, 2014, 372-384.
  14. Savić, A.; Misirlić-Denčić, S.; Dulović, M.; Mihajlović, Lj.E.; Jovanović, M.; Grgurić-Šipka, S.; Marković, I.; Sabo, T.J.: Synthesis, characterization and ROS-mediated cytotoxic action of novel (S,S)-1,3-propanediamine-N,N'-di-2-(3-cyclohexyl)propanoic acid and corresponding esters, Bioorg. Chem. 54 (2014) 73-80.
  15. Savić, A.; Baroud, A.A.; Grgurić-Šipka, S.: The new ruthenium(II)-bipyridyl complexes as potential PDT agent: Synthesis and characterization. Maced. J. Chem. Chem Eng. 33, (2014), 59-64.
  16. Zmejkovski, B.B.; Savić, A.; Poljarević, J.; Pantelić, N.; Aranđelović, S.; Radulović, S.; Grgurić-Šipka, S.; Kaluđerović, G.N.; Sabo, T.J.: Synthesis characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R2edda-type esters, Polyhedron, (2014), 80, 106-111.
  17. Ivanović, I.; Jovanović, K.K.; Gligorijević, N.; Radulović, S.; Arion, V.B.; Sheweshein, K.S.A.M.; Tešić, Ž.Lj.; Grgurić-Šipka, S: Ruthenium(II)-arene Complexes with Substitured Picolinato Ligands: Synthesis, Structure, Spectroscopic Properties and Antiproliferatice Activity. J. Organomet. Chem.  (2014), 749, 343-349.
  18. Mojić, M.; Savić, A.; Arion, V.; Bulatović, M.; Poljarević, J.M.; Miljković, Dj.; Sabo, T.J.; Mijatović, S.; Maksimović-Ivanić, D.; Grgurić-Šipka, S.: Synthesis, X-ray structure and strong in vitro activity of novel organoruthenium complexes. J. Organomet. Chem. (2014), 749, 142-149.
  19. Poljarević, J.M.; Krstić, M.P.; Grgurić-Šipka, S.; Sovilj, S.P.; Mišić, D.R., Sabo, T.J.: Platinum(IV) complexes with N-alkylphenotiazines: synthesis, characterization and antimicrobal activity. J. Coord. Chem. (2013), 66, 3760-3769.
  20. Mihajlović, Lj.E.; Stanković, D.; Poljarević, J.; Manojlović, D.; Sabo, T.J.; Grgurić-Šipka, S.: Electrochemistry and bioactivity relationship of Pt(IV) complexes with cyclohexyl functionalized ethylenedimanine-N,N'-diacetate types of ligands. Int. J. Electrochem. Sci. (2013), 8, 8433-8441.
  21. Ivanović, I.; Gligorijević, N.; Aranđelović, S.; Radulović, S; Roller, A.; Keppler, B.K.; Tešić, Ž. Lj.; Grgurić-Šipka, S.: New ruthenium(II) arene complexes bearing hydrazides or corresponding(thio)semicarbazones of 3- or 4-acetylpyridine: synthesis, characterization, crystal structure determination and antiproliferative activity. Polyhedron (2013), 61, 112-118.
  22. Rakić, G.M.; Grgurić-Šipka, S.; Kaluđerović, G.N.; Bette, M.; Filipović, L.;Aranđelović, S.; Radulović,S.; Tešić,Ž.Lj.:The synthesis, spectroscopic, X-ray characterization and in vitro cytotoxic testing results of activity of five new trans-platinum(IV) complexes with functionalized pyridines. Eur. J. Med. Chem. (2012), 55, 214-219.
  23. Misirlic Dencic, S.; Poljarevic, J.; Vilimanovich, U.; Bogdanovic, A.; Isakovic, A.J.; Stevovoc Kravic T.; Dulovic,; Zogovic, N.; Isakovic, A.M.; Grguric-Sipka, S,; Bumbasirevic V.; Sabo, T.; Trajkovic, V.; Markovic, I.: Cyclohexyl Analogues of Ethylenediamine Dipropanoic Acid Induce Caspase-Independent  Mitochondrial Apoptosis in Human Leukemic Cells. Chem. Res. Toxicol. (2012), 25, 931-939.
  24. Mihajlović, Lj.E.; Savić, A.; Poljarević, J.; Vučković, I.; Mojić, M.; Bulatović, M.; Maksimović-Ivanić, D.; Mijatović, S.; Kaluđerović, G.N.; Stošić-Grujičić, S.; Miljković, Đ.; Grgurić-Šipka, S.; Sabo, T.J.: Novel methylene modified cyclohexyl ethylenediamine-N,N'-diacetate ligands and their platinum(IV) complexes. Influence on biological activity. J. Inorg. Biochem. (2012), 109, 40-48.
  25. Gligorijević, N.; Aranđelović, S.; Filipović, L.; Dojčinović, B.; Jakovljević, K.; Janković, R.; Grgurić-Šipka, S.; Ivanović, I.; Radulović, S.; Tešić, Ž,Lj.: Picolinate ruthenium(II)-arene complex with  in vitro antiproliferative and antimetastatic properties: Comparision to a series of ruthenium(II)-p-arene complexes with similar structure. J. Inorg. Biochem. (2012), 108, 53-61.
  26. Miljković, Dj.; Poljarević, J.M.; Blaževski, J.; Petković, F.; Momčilović, M.; Nikolić, I.; Cvijetićanin, T.; Stošić-Grujičić, S.; Grgurić-Šipka, S.; Sabo, T.J. Novel octahedral Pt(IV) complex with di-n-propyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoato ligand exerts potent immunomodulatory effects. Eur. J. Med. Chem. (2012), 47, 194-201.
  27. Savić, Aleksandar; Dulović, Marija; Poljarević, Jelena P.; Misirlić-Denčić, Sonja; Jovanović, Maja; Bogdanović, Andrija; Trajković, Vladimir; Sabo, Tibor J.; Grgurić-Šipka, Sanja; Marković, Ivanka: Synthesis, and in vitro anticancer activity of ruthenium-cymene complexes with cyclohexyl derivatives of ethylenediamine-N,N'-diacetate type ligands. ChemMedChem. (2011), 6, 1884-1891.
  28. Rilak, A; Petrović B.; Grgurić-Šipka, S.; Tešić, Ž. Lj.; Bugarčić, Ž.: Kinetics and mechanism of the reactions of Ru(II)-arene complexes with some biologically relevant ligands. Polyhedron (2011), 30, 2339-2343.
  29. Krstić, Milena; Sovilj, Sovilj P.; Grgurić­-Šipka, Sanja; Radosavljević Evans, Ivana; Borozan, Sunčica; Santibanez, Juan Francisco: Synthesis, structural and spectroscopic characterization, in vitro cytotoxycity and in vivo activity as free radical scavengers of chlorido(p-cymene) complexes of ruthenium(II) containing N-alkylphenothiazines. Eur. J. Med. Chem. (2011), 46, 4168-4177.
  30. Ivanović, Ivanka; Grgurić-Šipka, Sanja; Gligorijević, Nevenka; Radulović, Siniša; Roller, Alexander; Tešić, Živorad Lj.; Keppler, Bernhard K.: X-ray structure and cytotoxic activity of picolinate ruthenium(II)-arene complex.  J. Serb. Chem. Soc. (2011), 76, 53-61.
  31. Krstić, Milena; Sovilj, Sovilj P.; Grgurić­-Šipka, Sanja; Radosavljević Evans, Ivana; Borozan, Sunčica; Santibanez, Juan Francisco; Kocić, Jelena: New ruthenium(II) complexes with N-alkylphenothiazines: synthesis, structure, in vivo activity as free radical scavengers and in vitro cytotoxycity. Eur. J. Med. Chem. (2010), 45, 3669-3676.
  32. Lazić, Jelena M.; Vučićević, Ljubica; Grgurić-Šipka, Sanja; Janjetović, Kristina; Kaludjerović, Goran N.; Misirkić, Maja; Gruden-Pavlović, Maja; Popadić, Dušan; Paschke, Reinhard; Trajković, Vladimir; Sabo, Tibor J.: Synthesis and in vitro Anticancer Activity of Octahedral Platinum(IV) Complexes with Cyclohexyl-Functionalized Ethylenediamine-N,N'-Diacetate-Type Ligands. ChemMedChem. (2010), 5, 881-889.
  33. Grgurić-Šipka, Sanja; Ivanović, Ivanka;Rakić, Gordana.;Todorović, Nina; Gligorijević, Nevenka; Radulović, Siniša; Arion, Vladimir B.; Keppler, Bernhard K.;Tešić, Živoslav Lj.: Ruthenium(II) arene Complexes with Functionalized Pyridines: Synthesis, Characterization and Cytotoxic Activity. Eur. J. Med. Chem. (2010), 45, 1051-1058.
  34. Grguric-Sipka, Sanja; Stepanenko, Iryna N.; Lazic, Jelena M.; Bartel, Caroline; Jakupec, Michael A.; Arion, Vladimir B.; Keppler, Bernhard K. Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin. Dalton Trans. (2009), 3334-3339.
  35. Rakić, Gordana M.; Grgurić-Šipka, Sanja; Kaluđerović, Goran N.; Gomez-Ruiz, Santiago; Bjelogrlić, Snežana M.; Radulović, Siniša S.; Tešić Živoslav Lj. Novel trans-dichloridoplatinum(II) complexes with 3- and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity. Eur. J. Med. Chem. (2009), 44, 1921-1925.
  36. Grgurić-Šipka, Sanja; Kowol, Christian R.; Valiahdi, Seied-Mojtaba; Eichinger, Rene; Jakupec, Michael A.; Roller, Alexander; Shova, Sergiu; Arion, Vladimir B.; Keppler, Bernhard K. Ruthenium(II) complexes of thiosemicarbazones: the first water-soluble complex with pH-dependent antiproliferative activity. Eur. J. Inorg. Chem. (2007), 2870-2878.
  37. Djinović, Vesna; Momčilović, Miljana; Grgurić-Šipka, Sanja; Trajković, Vladimir; Stojković, Marija Mostarica; Miljković, Djordje; Sabo, Tibor. Novel ruthenium complex K2[Ru(dmgly)Cl4]·2H2O is toxic to C6 astrocytoma cell line, but not to primary rat astrocytes. J. Inorg. Biochem. (2004), 98, 2168-2173.
  38. Grgurić-Šipka, Sanja R.; Vilaplana, Rosario A.; Perez, Jose M.; Fuertes, Miguel A.; Alonso, Carlos; Alvarez, Ysmael; Sabo, Tibor J.; Gonzalez-Vilchez, Francisco. Synthesis, characterization, interaction with DNA and cytotoxicity of the new potential antitumour drug cis-K[Ru(eddp)Cl2]. J. Inorg. Biochem. (2003), 97, 215-220.

Tue Sep 24 13:41:03 2019

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