[dr Dusan M. Sladic]

Hemijski fakultet, Studentski trg 12-16, Beograd
Katedra za organsku hemiju

Telefon:   011-3336679

Telefon (lokalni):   679

Kabinet:   475

E-mail:   dsladic@chem.bg.ac.rs

Lični podaci

Datum i mesto rođenja: 3. 3. 1958, Zemun. Neoženjen. Jezici koje koristi: srpski (maternji), engleski, nemački, francuski i italijanski.

Obrazovanje i usavršavanja

1976-1980: Osnovne studije - Hemijske nauke / Prirodno-matematički fakultet (Beograd)

1980-1986: Magistratura - Hemijske nauke / Prirodno-matematički fakultet (Beograd)

1986-1992: Doktorat - Hemijske nauke / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

Kretanje u službi

1980: Student saradnik / Prirodno-matematički fakultet (Beograd)

1980-1982: Student saradnik / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1982: Asistent pripravnik / Prirodno-matematički fakultet (Beograd)

1982-1990: Asistent pripravnik / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1990: Asistent / Prirodno-matematički fakultet (Beograd)

1990-1994: Asistent / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

1992-2003: Docent / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2003-2008: Vanredni profesor / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

2008: Redovni profesor / Univerzitet u Beogradu - Hemijski fakultet (Beograd)

Oblasti naučnog interesovanja

Bioorganska hemija (mehanizam delovanja i odnos struktura/aktivnost antitumorskih agenasa, biološke oksido-redukcije, reaktivnost i biološka aktivnost hinona i fenola, interakcije malih molekula i bioloških makromolekula, marinski prirodni proiővodi, lektini, struktura i biološka aktivnost kompleksnih jedinjenja).

Nagrade i priznanja

1993: Medalja Srpskog hemijskog društva za pregalaštvo i uspeh u nauci

1993: Nagrada kompanije ICN Galenika za doktorsku disertaciju

2007: Medalja Srpskog hemijskog društva za izuzetne rezultate u nastavi

Ostale aktivnosti

Član Srpskog hemijskog društva od 1980. - Sekcija za organsku hemiju. Član Predsedništva i Upravnog odbora; predsednik Sekcije.

Predsednik Saveta Hemijskog fakulteta od 14. 10. 2015. do 10. 4. 2016.

Šef Katedre za organsku hemiju od 1. 8. 2016. do 31. 7. 2019.

Šef Katedre za organsku hemiju od 1. 8. 2019. do 14. 7. 2022.

Zamenik predsednika Etičke komisije od 12. 7. 2021.

Šef Katedre za organsku hemiju od 14. 7. 2022. do 30. 9. 2023.

Angažman u nastavi

Učešće u naučnoistraživačkim projektima

Aktivni projekti:

Završeni projekti:

  • 2011: Interakcije prirodnih proizvoda, njihovih derivata i kompleksnih jedinjenja sa proteinima i nukleinskim kiselinama – 172055   (rukovodilac projekta)
    vrsta projekta:   domaći fundamentalni
    projekat finansira:   Ministarstvo za nauku i tehnološki razvoj Republike Srbije (Beograd)
  • 2012: Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells – CMST COST Action CM1106
    vrsta projekta:   međunarodni
    projekat finansira:   Evropska unija (Brisel, Belgija)

Brojevi za identifikaciju autora

Izabrane reference

Knjige i revijalni radovi / Books and reviews:

  1. D. Sladić, M.J. Gašić, Reactivity and biological activity of the marine sesquiterpene hydroquinone avarol and related compounds from sponges of the order Dictyoceratida. (Revijski rad), Molecules 11, 1 (2006)

Izabrani radovi / Selected papers:

  1. Božić, Tatjana; Sladić, Dušan; Zlatović, Mario; Novaković, Irena; Trifunović, Snežana; Gašić, Miroslav J. Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones. Journal of the Serbian Chemical Society (2002), 67(8-9), 547-551
  2. Kamenarska, Z.; Gašić, M. J.; Zlatović, M.; Rašovic, A.; Sladić, D.; Kljajić, Z.; Stefanov, K.; Seizova, K.; Najdenski, H.; Kujumgiev, A.; Tsvetkova, I.; Popov, S. Chemical composition of the brown alga Padina pavonia (L.) Gaill. from the Adriatic Sea. Botanica Marina (2002), 45(4), 339-345
  3. Pajić, Ivana; Kljajić, Zoran; Dogović, Nikola; Sladić, Dušan; Juranić, Zorica; Gašić, Miroslav J. A novel lectin from the sponge Haliclona cratera: isolation, characterization and biological activity. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP (2002), 132(2), 213-21
  4. Trifunović, Srećko R.; Marković, Zorica; Sladić, Dušan; Andjelković, Katarina; Sabo, Tibor; Minić, Dragica. The synthesis and characterization of nickel(II) and copper(II) complexes with the polydentate dialkyl dithiocarbamic acid ligand 3-dithiocarboxy-3-aza-5-aminopentanoate. Journal of the Serbian Chemical Society (2002), 67(2), 115-122
  5. Pfendt, Lidija B.; Popović, Gordana V.; Damjanović, Tatjana Z.; Sladić, Dušan M.. Protolytic equilibria of bromazepam. Journal of the Serbian Chemical Society (2002), 67(3), 187-195
  6. Popović, G. V.; Sladić, D. M.; Stefanović, V. M.; Pfendt, L. B. Study on protolytic equilibria of lorazepam and oxazepam by UV and NMR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis (2003), 31(4), 693-699
  7. Novaković, Irena; Vujčić, Zoran; Božić, Tatjana; Božić, Natasa; Milosavić, Nenad; Sladić, Dušan. Chemical modification of b-lactoglobulin by quinones. Journal of the Serbian Chemical Society (2003), 68(4-5), 243-248
  8. Andjelković, Katarina; Howing, Jonas; Tellgren, Roland; Jeremić, Dejan; Ivanovicć-Burmazović, Ivana; Sladić, Dušan. Synthesis and Structural Characterization of the Co(III) Complex with 2'-[1-(2-Pyridinyl)-Ethylidene]-Oxamohydrazide (Hapsox): the Crystal Structure of Bis-2'-[1-(2-Pyridinyl)-Ethylidene]bis(Oxamohydrazido) Cobalt(III) Perchlorate, [Co(apsox)2]ClO4. Journal of Coordination Chemistry (2003), 56(7), 611-622
  9. Bacchi, Alessia; Pelizzi, Giancarlo; Jeremić, Dejan; Sladić, Dušan; Gruden-Pavlović, Maja; Andjelković, Katarina. Synthesis and structural characterization of copper(II) complexes with the 2'-[1-(2-pyridinyl)ethylidene]oxalohydrazide ligand. Transition Metal Chemistry (Dordrecht, Netherlands) (2003), 28(8), 935-938
  10. Natić, Maja; Tešić, Živoslav; Anđelković, Katarina; Brčeski, Ilija; Radulović, Siniša; Manić, Sandra; Sladić, Dušan. Synthesis and Biological Activity of Pd(II) and Cu(II) Complexes with Acylhydrazones of Usnic Acid. Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry (2004), 34(1), 101-113
  11. Minić, D.; Jakovljević, G.; Sladić, D.; Andjelković, K. Investigation of thermal stability and kinetic studies of transition metal complexes with the condensation product of 2,6-diacetylpyridine and semioxamazide. Materials Science Forum (2004), 453-454(Progress in Advanced Materials and Processes), 567-572
  12. Anđelković, Katarina; Jakovljević, Gordana; Zlatović, Mario; Tešić, Živoslav; Sladić, Dušan; Howing, Jonas; Tellgren, Roland. Synthesis and characterization of zinc(II), palladium(II) and platinum(II) complex with 2'-[1-(2-pyridinyl)ethylidene]oxamohydrazide. The crystal structure of bis2'-[1-(2-pyridinyl)ethylidene]oxamohydrazido zinc(II) trihydrate. Journal of the Serbian Chemical Society (2004), 69(8-9), 651-660
  13. Sladić, Dušan; Novaković, Irena; Vujčić, Zoran; Božić, Tatjana; Božić, Nataša; Milić, Dragana; Šolaja, Bogdan; Gašić, Miroslav J. Protein covalent modification by biologically active quinones. Journal of the Serbian Chemical Society (2004), 69(11), 901-907
  14. Anđelković, Katarina; Sladić, Dušan; Bacchi, Alessia; Pelizzi, Giancarlo; Filipović, Nenad; Rajković, Miloš. Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate. Transition Metal Chemistry (Dordrecht, Netherlands) (2005), 30(2), 243-250
  15. Vojić, Mirjana P.; Popović, Gordana V.; Sladić, Dušan M.; Pfendt, Lidija B. Protolytic equilibria in homogeneous and heterogeneous systems of ketoconazole and its direct spectrophotometric determination in tablets. Journal of the Serbian Chemical Society (2005), 70(1), 67-78
  16. Lazić, M. J.; Anđelković, K. K.; Sladić, D. M.; Tešić, Z. L.; Radulović, S. S. The evaluation of cytotoxic activity of planar pentadentate ligand 2',2'''-(2,6-pyridindiyldiethylidyne) dioxamohydrazide dihydrate (H2LxH2O) and its metal coordination complexes; pitfalls in the use of the MTT-assay. Journal of Experimental & Clinical Cancer Research (2005), 24(1), 63-68
  17. Prodanović, Radivoje M.; Milosavić, Nenad B.; Sladić, Dušan; Veličković Ćirković, Tanja; Vujčić, Zoran. Synthesis of hydroquinone-a-glucoside by a-glucosidase from baker's yeast. Biotechnology Letters (2005), 27(8), 551-554
  18. Todorović, T.; Andjelković, K.; Sladić, D.; Jeremić, D.; Minić, D. Investigation of thermal stability of Zn(II), Pt(II) and Pd(II) complexes with (E)-2-oxo-2-N-[1-(pyridin-2-yl)ethylidene]hydrazinoacetamide. Materials Science Forum (2005), 494 375-379
  19. Prodanović, Radivoje; Milosavić, Nenad; Sladić, Dušan; Zlatović, Mario; Božić, Branislav; Veličković Ćirković, Tanja; Vujčić, Zoran. Transglucosylation of hydroquinone catalysed by a-glucosidase from baker's yeast. Journal of Molecular Catalysis B: Enzymatic (2005), 35(4-6), 142-146
  20. Kapetanović, Radomir; Sladić, Dušan; Popov, Simeon; Zlatović, Mario; Kljajić, Zoran; Gašić, Miroslav J. Sterol composition of the adriatic sea algae Ulva lactuca, Codium dichotomum, Cystoseira adriatica and Fucus virsoides. Journal of the Serbian Chemical Society (2005), 70(12), 1395-1400
  21. Radulović, Vesna; Bacchi, Alessia; Pelizzi, Giancarlo; Sladić, Dušan; Brčeski, Ilija; Andjelković, Katarina. Synthesis, Structure, and Antimicrobial Activity of Complexes of Pt(II), Pd(II), and Ni(II) with the Condensation Product of 2-(Diphenylphosphino)benzaldehyde and Semioxamazide. Monatshefte fuer Chemie (2006), 137(6), 681-691
  22. Lazić, M.; Radulović, S.; Todorović, T.; Sladić, D.; Tešić, Z.; Andjelković, K. Evaluation of cytotoxic activity of d-metal complexes with hydrazone ligands. Materials Science Forum (2006), 518(Recent Developments in Advanced Materials and Processes), 513-518
  23. Todorović, Tamara R.; Bacchi, Alessia; Pelizzi, Giancarlo; Juranić, Nenad O.; Sladić, Dušan M.; Brčeski, Ilija D.; Anđelković, Katarina K. Synthesis and characterization of Zn(II) and Cd(II) complexes with 2,6-diacetylpyridine-bis(selenosemicarbazone). Crystal structure of a Ni(II) complex with a modified 2,6-diacetylpyridine-bis(selenosemicarbazone). Inorganic Chemistry Communications (2006), 9(8), 862-865
  24. Malešević, Nevenka; Srdić, Tatjana; Radulović, Siniša; Sladić, Dušan; Radulović, Vesna; Brčeski, Ilija; Anđelković, Katarina. Synthesis and characterization of a novel Pd(II) complex with the condensation product of 2-(diphenylphosphino)benzaldehyde and ethyl hydrazinoacetate. Cytotoxic activity of the synthesized complex and related Pd(II) and Pt(II) complexes. Journal of Inorganic Biochemistry (2006), 100(11), 1811-1818
  25. Penov Gaši, Katarina M. ; Djurendić Brenesel, Maja Dj. ; Djurendić, Evgenija A.; Sakač, Marija N.; Čanadi, Janoš J.; Daljev, Jovana J.; Armbruster, Thomas; Andrić, Silvana; Sladić, Dušan M.; Božić, Tatjana T.; Novaković, Irena T.; Juranić, Zorica D. Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives. Steroids (2007), 72(1), 31-40
  26. Tsoukatou, Maria; Marechal, Jean Philippe; Hellio, Claire; Novaković, Irena; Tufegdžić, Srđan; Sladić, Dušan; Gašić, Miroslav J.; Clare, Anthony S.; Vagias, Constantinos; Roussis, Vassilios. Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms. Molecules (2007), 12(5), 1022-1034
  27. Todorović, Tamara R.; Bacchi, Alessia; Juranić, Nenad O.; Sladić, Dušan M.; Pelizzi, Giancarlo; Božić, Tatjana T.; Filipović, Nenad R.; Anđelković, Katarina K. Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II). Polyhedron (2007), 26(13), 3428-3436
  28. Filipović, N. R.; Todorović, T. R.; Sladić, D. M.; Novaković, I. T.; Jeremić, D. A.; Andjelković, K. K. Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands. Materials Science Forum (2007), 555(Research Trends in Contemporary Materials Science), 423-427