Course code:
401B2		 Course name:
Biochemistry of Proteins and Nucleic Acids

Academic year:

2024/2025.

Attendance requirements:

101M2 + 301B2

ECTS:

12

Study level:

basic academic studies

Study program:

Biochemistry: 2. year, winter semester, compulsory course

Teacher:

Natalija Đ. Polović, Ph.D.
full professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Assistants:

Jelica R. Milošević, Ph.D.
assistant with PhD, Faculty of Chemistry, Studentski trg 12-16, Beograd

Natalija S. Andrejević
junior research assistant, Faculty of Chemistry, Studentski trg 12-16, Beograd

Hours of instruction:

Weekly: four hours of lectures + one hour of exercises + six hours of labwork (4+1+6)

Goals:

The goal of this course is to help students acquire fundamental knowledge of the structure and function of proteins and nucleic acids. Students should understand the connection between the structure and function of proteins and nucleic acids. This course provides students with a foundation for biochemistry and molecular biology courses in the subsequent years of their studies. Students will become familiar with the basic techniques and methods used for isolation and characterization of proteins and nucleic acids and they will acquire the basic skills necessary for working in a biochemical laboratory.

Outcome:

Understanding the structure of proteins and nucleic acids, the connection between the structure and activity of proteins and the relationship between proteins and nucleic acids at the level of undergraduate studies. Acquired basic skills necessary for working in a biochemical laboratory and developed initial understanding of experimental work with proteins and nucleic acids.

Teaching methods:

Lectures, experimental exercises, theory exercises, individual and group work with students on consolidating the course units.

Extracurricular activities:

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Coursebooks:

Main coursebooks:

  1. Natalija Polović: Osnove biohemije, 2021. ISBN: 978-86-7220-106-2
  2. Vesna Niketic: Principi strukture i aktivnosti proteina
  3. Vesna Niketic: Uputstva za vežbe
  4. D. Voet, J. Voet: Biochemistry, 2004.
  5. C. R. Calladine, H. R. Drew: Understanding DNA

Supplementary coursebooks:

  • Natalija Polović: PPT presentations
  • D. L. Nelson, M. M. Cox, Lehninger: Principles of Biochemistry
  • J. M. Claviere, C. Notredame: Bioinformatics for Dummies, Wiley, 2007.
  • Selected original papers from current literature
  • Web pages relevant to this course

Additional material:

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  Course activities and grading method

Lectures:

2 points (4 hours a week)

Exercises:

3 points (1 hour a week)

Labwork:

15 points (6 hours a week)

Colloquia:

20 points

Written exam:

30 points

Oral exam:

30 points