Course code:
201B2		 Course name:
Organic Chemistry 1

Academic year:

2024/2025.

Attendance requirements:

There are no requirements.

ECTS:

11

Study level:

basic academic studies

Study program:

Biochemistry: 1. year, summer semester, compulsory course

Teacher:

Aleksandra D. Mitrović, Ph.D.
assistant professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Assistants:

Vojislava E. Poštić
teaching assistant, Faculty of Chemistry, Studentski trg 12-16, Beograd

Andrej J. Kukuruzar
teaching assistant, Faculty of Chemistry, Studentski trg 12-16, Beograd

Hours of instruction:

Weekly: four hours of lectures + three hours of exercises + four hours of labwork (4+3+4)

Goals:

The goal of this course is to help students master the concepts of the structure and the types of bonding of organic compounds, the nomenclature of organic molecules, the basic concepts of stereochemistry and the chemical reactivity of certain classes of organic compounds, such as: alkanes, alkenes, alkynes, alkyl halides, alcohols and thiols, ethers and sulfides, and to master the techniques used for purifying, obtaining and identifying organic compounds.

Outcome:

Upon completing this course, students will be able to name organic compounds; they will have mastered the concepts of acidity and alkalinity and the types of bonding. They will be able to predict stereochemical implications of the reactions of organic compounds and describe the mechanisms of some typical organic reactions (addition, nucleophilic substitution, elimination, molecular rearrangement).

Teaching methods:

Lectures, experimental exercises, theory exercises, revising and consolidating the course units through quizzes which are organized once or twice a week.

Extracurricular activities:

Homework assignments - weekly.

Coursebooks:
  • P. Volhart, N. Šor: Organska hemija - struktura i funkcija, Data status, Nauka, Beograd
  • V. Pavlović, R. Marković, A. Milovanović: Praktikum iz organske hemije (reviewed text)
  • The teacher’s notes and the presentations which accompany the lectures in electronic form (PPT or PDF)

Additional material:

—

  Course activities and grading method

Lectures:

0 points (4 hours a week)

Syllabus:

  1. Introduction to organic chemistry
  2. Structure and properties of organic molecules
  3. Alkanes and cycloalkanes
  4. Studying chemical reactions
  5. Stereochemistry I
  6. Stereochemistry II
  7. Introduction to alkyl halides, alcohols, ethers, thiols and sulfides
  8. Alkyl halides: nucleophilic substitution and elimination
  9. Alkenes
  10. Reactions of alkenes
  11. Alcohols and thiols I: structure and synthesis
  12. Alcohols II: reactions of alcohols
  13. Ethers, epoxides, glycols and sulfides
  14. Alkynes
  15. Introduction to spectroscopy (a short overview)

Exercises:

0 points (3 hours a week)

Labwork:

10 points (4 hours a week)

Syllabus:

  1. Crystallization and determination of the melting point.
  2. Distillation (simple and fractional).
  3. Steam distillation and distillation under reduced pressure.
  4. Chromatography (column and thin-layer).
  5. Extraction and isolation (isolation of caffeine from tea, vacuum sublimation).
  6. Testing the solubility of organic substances and qualitative organic analysis.
  7. Alkanes, cycloalkanes and alkenes (obtaining methane and cyclohexene, reactions, oxidation of oleic acid).
  8. Alkyl halides (obtaining butyl bromide and tert-butyl chloride, nucleophilic substitution reactions).
  9. Alkynes and alcohols (obtaining acetylenes and acetylides, oxidation of alcohols and other reactions).
  10. The analysis of an unknown organic compound.
  11. and 12. Stereochemistry (the concept of a chiral object, working with models).

Colloquia:

30 points

Written exam:

60 points