Course code:
1061B
Course name:
Cell Biology

Academic year:

2012/2013.

Attendance requirements:

There are no requirements.

ECTS:

9

Study level:

basic academic studies

Study program:

Biochemistry: 1. year, winter semester, compulsory course

Teacher:

Mirela M. Ukropina, Ph.D.
associate professor, Faculty of Biology, Studentski trg 3, Beograd

Assistants:

Hours of instruction:

Weekly: five hours of lectures + one hour of exercises + two hours of labwork (5+1+2)

Goals:

Introducing with basic principles of cell organization, dynamics of the mutual relation and structural-functional characteristics of cell organelles. Students should acquire basic knowledge on diversity of intracellular processes, mode of cell to cell comunication and cell association in tissues.

Outcome:

Acquired basic knowledge on diversity of intracellular processes, mode of cell to cell comunication and cell association in tissues.

Teaching methods:

Lectures,exercises,labwork,semester paper(s).

Extracurricular activities:

Coursebooks:

  • Др Нада М. Шербан: Ћелија – структуре и облици (Завод за уџбенике и наставна средства, Београд, 2005)
  • Др Нада М. Шербан: Основи хистологије (радна верзија уџбеника, 2006.) или
  • Др Нада М. Шербан: Покретне и непокретне ћелије (Савремена администрација, Београд, 1995)

Additional material:

http://www.chem.bg.ac.rs/~mirela

  Course activities and grading method

Lectures:

10 points (5 hours a week)

Syllabus:

1. week: Introduction in Cell biology. Different types of microscopes as tools in cell and tissue research. General principles of cell organiztion.

2. week: Membrane - structure, function and chemistry. Membrane transport.

3. week: Organelles involved in processes of synthesis - ribosomes, endoplasmic reticulum, Golgi apparatus.

4. week: Degradative compartments in the cell: endosomes, lysosomes. Autophagy. Heterophagy. Peroxisomes. Vаcuoles in plant cells.

5. week: Mitochondria - structure and function. Unususal roles for mitochondria in some cell types. Plastides - photosynthetic and non-photosynthetic plastides.

6. week: Intracellular deposits, inclusions. Cytoskeleton - actin filaments and associtaed proteins. Intermediate filaments.

7. week: Cytoskeleton - microtubules, centrioles, basal bodies. Cilia. Flagella. Nucleus, nuclear envelope, nuclear pore complex, nuclear lamina, nuclear matrix. Nucleolus.

8. week: Chromatin packing - interphase chromosomes, mitotic chromosomes. Cell and its environment. The extracellular matrix.

9. week: Cell to cell adhesion and communication. Plant cell wall. Bacterial cell walls. Cell cycle - definition, variation, control system. Cell aging. Cell death.

10. week: Test.

11. week: Cell division. Mitosis. Meiosis. Introduction in tissue biology. Epithelial tissue -classification.

12. week: Types of glandular epithelia. Exocrine and endocrine secreting cells. General structure and function of connestive tissue. Classification.

13. week: Connective tissue proper. Blood. Adipose tissue. Cartilage. Bone.

14.week: General characteristics of mucular tissue. Striated muscle cell. Smooth muscle cell. Cardiac muscle cell. Nervous tissue. Neuron - types and cytological characteristics. Supporting cells of the nervous system. Communications between nerve cells.

15. week: Test.

Exercises:

10 points (1 hour a week)

Labwork:

10 points (2 hours a week)

Colloquia:

20 points

Oral exam:

50 points