Course code: 211H2 |
Course name: Organic Synthesis 1 |
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Academic year: |
2024/2025. |
Attendance requirements: |
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ECTS: |
7 |
Study level: |
basic academic studies |
Study program: |
Chemistry: 3. year, summer semester, compulsory course |
Teachers: |
Radomir N. Saičić, Ph.D. Filip J. Bihelović, Ph.D. |
Assistants: |
Filip T. Đurković Andrej J. Kukuruzar |
Hours of instruction: |
Weekly: two hours of lectures + four hours of labwork (2+0+4) |
Goals: |
During the course the student should acquire both the theoretical knowledge in the field of organic synthesis and the manipulative skills for independent realization of the experimental procedures for the preparation of organic compounds. The course ORGANIC SYNTHESIS 1 includes functional group transformations in organic compounds. Through the lectures, students get acquainted with methods for performing oxidations, reductions, halogenations and methods for the introduction of heteroatoms into organic molecules. The course includes explanations of organic reactions, but the focus is on the preparative, practical aspect, which includes the right choice of reagents and reaction conditions in order to achieve the desired transformation with a high yield in a safe, economical and ecologically acceptable way. The main goal is to enable students to theoretically and practically perform the following types of preparative reactions: 1) oxidations, 2) reductions, 3) halogenations, 4) electrophilic aromatic substitutions by heteroatom reagents, 5) other functional transformations pertinent to organic synthesis. In addition, students should acquire routine in applying techniques of monitoring organic reactions, isolation and purification of products (chromatographic methods, distillations, crystallizations etc.), as well as in characterizing the obtained compounds. |
Outcome: |
The ability to independently realize basic functional group transformations in organic chemistry at the preparative level. |
Teaching methods: |
Lectures, experimental exercises. |
Extracurricular activities: |
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Coursebooks: |
Main coursebooks:
Supplementary coursebooks:
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Additional material: |
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Course activities and grading method |
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Lectures: |
8 points (2 hours a week) Syllabus:
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Labwork: |
22 points (4 hours a week) Syllabus: Laboratory classes are of experimental nature and they include independent realization of 6 (six) preparations from the list in the Handbook and from the chemical literature.These preparations are experimental illustrations of the course units presented in the lectures and they include the practical examples of synthesizing organic compounds using the reactions of oxidation, reduction, halogenation, aromatic substitution, etc. In addition, during the realization of the preparations, students get acquainted with various techniques of isolation and purification of organic compounds, such as distillation under reduced pressure, steam distillation, continuous distillation, crystallization, etc. and are trained to routinely use these techniques in laboratory. One laboratory class deals with searching for scientific information and involves teaching students how to use scientific journals and databases. |
Colloquia: |
0 points Remarks: Students who have not passed the exam until the beginning of the course in the next school year are obliged to attend the lectures again. |
Written exam: |
70 points Remarks: Students take a written exam. In order to get a passing grade, a student has to achieve at least 50% of the points (50% of the total number of points) in the written test. |