Faculty of Chemistry, Studentski trg 12-16, Beograd
Department of Organic Chemistry
Phone: 011-3282537
Office: 471
Laboratory: 470, 427, 416
E-mail: rsaicic@chem.bg.ac.rs
Personal data
Born: October 31, 1961, Belgrade.
Education and qualifications
1979-1983: Undergraduate studies - Chemistry / Prirodno-matematički fakultet (Belgrade, Serbia)
1983-1987: Master of science studies - Chemistry / Prirodno-matematički fakultet (Belgrade, Serbia)
1988-1991: Doctoral academic (PhD) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
1995-1996: Postdoctoral studies / Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS) (Gif-sur-Yvette, France)
History of employment
1984: Graduate assistant / Prirodno-matematički fakultet (Belgrade, Serbia)
1984-1988: Graduate assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
1989: Assistant / Prirodno-matematički fakultet (Belgrade, Serbia)
1989-1993: Assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
1992-1997: Assistant professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
1997-2002: Associate professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
2002: Full professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)
Scientific interest
Organic chemistry, organic synthesis, medicinal chemistry.
A short review of our research work.
Awards and merits
1987: October prize of the City of Belgrade for students (for the best MS thesis)
1995: Medal for the scientific zeal and success of the Serbian Chemical Society
2007: Award of the City of Belgrade for the best scientific achievement in 2007
Other activities
Corresponding member of Serbian Academy of Sciences and Arts from November 1, 2012 to November 8, 2018 - Department of chemical and biological sciences.
Full member of Serbian Academy of Sciences and Arts from November 8, 2018 - Department of chemical and biological sciences.
Member of Serbian Chemical Society from 1984 - Section for organic chemistry; Section for medicinal chemistry.
Head of the Department of Organic Chemistry from 1999 till 2003.
Member of the Committee for Strategy of Scientific Development of the Faculty of Chemistry from December 10, 2020.
Chairman of the Ethical Committee from July 12, 2021.
Head of the Department of Organic Chemistry from October 1, 2023.
2005: Visiting researcher at ICSN-CNRS, Gif-sur-Yvette, France
Educational activities
- Organic Synthesis 1 (211H2)
- Organic Synthesis 2 (212H2)
- Synthesis of Complex Organic Molecules (255H2)
- New Synthetic Methods (272H2)
- Organometallic Chemistry (771H2)
Participation in research projects
Active projects:
- 2020-2022: Small Molecule Anti-RNA-virus Therapy. Repurposing Iminosugars and Chloroquine Analogues Against COVID-19 (SMART Repurposing) – 7547552 (principal investigator)
project type: COVID-19
project is funded by: Science Fund of the Republic of Serbia (Belgrade, Serbia) - 2022-2025: New Synthetic Methods and their Applications for Rapid Total Syntheses of Complex Natural Products and Bioactive Molecules (New SMART Synthesis) – 7750119 (principal investigator)
project type: IDEJE
project is funded by: Science Fund of the Republic of Serbia (Belgrade, Serbia)
Finished projects:
- 2011: The development of new synthetic methods and their application in syntheses of natural products and biologically active compounds – 172027 (principal investigator)
project type: National Fundamental Research Projects
project is funded by: Ministry of Science and Technological Development (Belgrade, Serbia) - 2014-2015: – 451-03-2802-¸ż 1/191 (principal investigator)
project type: National Innovation Projects - 2011-2015: – 172027-¸Ć (principal investigator)
project type: National Innovation Projects - 2017: – 391-00-16/2017-16/2 ¸ż
project type: National Innovation Projects
project is funded by: Ministarstvo prosvete, nauke i tehnološkog razvoja (Belgrade, Serbia) - 2019: Donation Contract – Donation Contract - No 937012 (principal investigator)
project type: International
project is funded by: European Commission - Joint Researc Centre (Brisel, Belgium)
Author identification numbers
- ORCID: 0000-0003-3653-8294
- ResearcherID: Q-5483-2016
- Scopus: 7003983328
- Faculty of Chemistry Repository Cherry
Representative references
Knjige i revijalni radovi / Books and reviews:
- R. N. Saicic: Protecting group-free syntheses of natural products and biologically active compounds, Tetrahedron 2014, 70, 8183-8218.
- R. N. Saičić: Sintetičke slobodno-radikalske reakcije: stvaranje veze ugljenik-ugljenik, Univerzitet u Beogradu, Hemijski fakultet i I. H. T. M.- Centar za hemiju, Beograd, 1995.
- R. N. Saičić: Potassium O-ethyl xanthate, in: Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley InterScience (www3.interscience.wiley.com), 2005, DOI: 10.1002/047084289X.rn00544.
- R. N. Saicic, V. Maslak: 4-(Bromomethyl)-1,3-dioxol-2-one, in: Electronic Encyclopedia of Reagents for Organic Synthesis, Wiley InterScience (www3.interscience.wiley.com), 2014, published online 27 May, 2014, DOI: 10.1002/047084289X.rn01702.
Izabrani radovi / Selected papers:
- M. Trajkovic, V. Balanac, Z. Ferjancic, R. N. Saicic: Total synthesis of (+)-swainsonine and (+)-epi-swainsonine, RSC Adv. 2014, 4 (96), 53722-53724.
- B. Vulovic, M. Gruden-Pavlovic, R. Matovic, R. N. Saicic: Substrate stereocontrol in the intramolecular organocatalyzed Tsuji-Trost reaction: enantioselective synthesis of allokainates, Org. Lett. 2014, 15, 34-37.
- J. Marjanovic, V. Divjakovic, R. Matovic, Z. Ferjancic, R. N. Saicic: Double asymmetric induction in organocatalyzed aldol reaction: Total synthesis of (+)-2-epi-hyacinthacine A2 and (-)-3-epi-hyacinthacine A1, Eur. J. Org. Chem. 2013, 5555-5560.
- F. Bihelović, I. Karadžić, R. Matović and R. N. Saičić: Total synthesis and biological evaluation of (-)-atrop-abyssomicin C, Org. Biomol. Chem. 2013, 11, 5413-5424
- M. Trmčić, R. Matović, G. Tovilović, B. Ristić, V. Trajković, Z. Ferjančić and R. N. Saičić: A Novel C,D-Spirolactone Analogue of Paclitaxel: Autophagy Instead of Apoptosis as a Previously Unknown Mechanism of Cytotoxic Action for Taxoids, Org. Biomol. Chem. 2012, 10, 4933-4942.
- M. Trajković, Z. Ferjančić, R. N. Saičić: A convenient procedure for the preparation of the Garner aldehyde, Tetrahedron: Asymmetry 2012, 23, 602-604.
- F. Bihelović, R. N. Saičić: Total synthesis of (-)-atrop-abyssomicin C, Angew. Chem. Int. Ed. 2012, 51, 5687-5691.
- M. Trajković, Z. Ferjančić and R. N. Saičić: An aldol approach to the enantioselective synthesis of (-)-oseltamivir phosphate, Org. Biomol. Chem. 2011, 9, 6927-6929.
- M. Bigović, V. Maslak, Z. Tokić-Vujošević, V. Divjaković and R. N. Saičić: A useful synthetic equivalent of a hydroxyacetone enolate, Org. Lett. 2011, 13, 4720-4723.
- B. Vulovic, F. Bihelović, R. Matović and R. N. Saičić: Organo-catalyzed Tsuji-Trost reaction: a new method for the closure of five- and six-membered rings, Tetrahedron 2009, 65, 10485-10494.
- V. Maslak, Z. Tokic-Vujosevic, Z. Ferjancic and R. N. Saicic: A useful synthetic equivalent of an acetone enolate, Tetrahedron Lett. 2009, 50, 6709-6711.
- F. Bihelović, R. Matović, B. Vulović and R. N. Saičić: Organo-catalyzed cyclizations of pi-allylpalladium complexes: a new method for the construction of five- and six-membered rings, Org. Lett. 2007, 9, 5063-5066.
- A. Ivković, M. Manojlović, R. Matović, Z. Tokić-Vujošević and R. N. Saičić: Ring closing metathesis/fragmentation route to (Z)-configured medium ring cycloalkenes. Total synthesis of (±)-Periplanone, J. Org. Chem. 2006, 71, 9411-9419.
- Z. Ferjančić, R. Matović, Ž. Čeković, Y. Jiang, J. P. Snyder, V. Trajković and R. N. Saičić: Synthesis, biology and modeling of C-4 carbonyl C,D-seco-taxoid, Tetrahedron 2006, 62, 8503-8514.
- V. Maslak, R. Matović and R. N. Saičić: Reaction of silyl ketene acetals with epoxides: a new method for the synthesis of γ-butanolides, Tetrahedron 2004, 60, 8957-8966.
- A. Ivković, R. Matović and R. N. Saičić: Ring closing metathesis/fragmentation route to geometrically defined medium ring cycloalkenes: total synthesis of (±)-Periplanone C, Org. Lett. 2004, 6, 1221-1224.
- S. Milićević, R. Matović and R. N. Saičić: Stereoselective syntheses of (-)-cytoxazone and (+)-epi-cytoxazone, Tetrahedron Lett. 2004, 45, 955-957.
- Z. Ferjančić, Ž. Čeković, R. N. Saičić: Free radical domino reactions in the synthesis of small ring compounds: multiple annulation of cyclopropane containing polycycles, Comptes Rendus de l’Academie des sciences Serie IIc Chemistry 2001, 4, 599-610.
- G. Lalić, Ž. Petrovski, D. Galonić, R. Matović and R. N. Saičić: Alkylation of carbonyl compounds in the TiCl4-promoted reaction of trimethylsilyl enol ethers with epoxides, Tetrahedron 2001, 57, 583-591; Methods in Organic Synthesis 45851.
- R. N. Saičić, R. Matović: An efficient semisynthesis of 7-deoxypaclitaxel from taxine, J. Chem. Soc., Perkin Trans. 1, 2000, 59-65.