[dr Filip J. Bihelovic]

Faculty of Chemistry, Studentski trg 12-16, Beograd
Department of Organic Chemistry

Phone:   011-3336658

Phone (local):   658

Office:   428

E-mail:   filip@chem.bg.ac.rs

Personal data

Born: August 19, 1981, in Belgrade

Education and qualifications

2000-2005: Undergraduate studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2007-2011: Doctoral academic (PhD) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

History of employment

2006-2008: Teaching assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2008-2014: Assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2014-2019: Assistant professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2019: Associate professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

Scientific interest

Organic chemistry; Total synthesis; Organometallic chemistry; Asymmetric organocatalysis; Demonstration chemistry experiments

Awards and merits

2022: Thieme Chemistry Journals Award

Educational activities

Participation in research projects

Active projects:

Finished projects:

  • 2011: The development of new synthetic methods and their application in syntheses of natural products and biologically active compounds – 172027
    project type:   National Fundamental Research Projects
    project is funded by: Ministry of Science and Technological Development (Belgrade, Serbia)
  • 2017: – 391-00-16/2017-16/2 ¸¿   (principal investigator)
    project type:   National Innovation Projects
    project is funded by: Ministarstvo prosvete, nauke i tehnolo¹kog razvoja (Belgrade, Serbia)
  • 2016-2017: Total synthesis and biological activity of alstoscholarisin A derivatives – ¿ÞÚàÕÝØ áÕ ×Ð ÝÐãÚã   (principal investigator)
    project type:   National Development Projects
    project is funded by:  Filip Moris (Belgrade, Serbia)

Author identification numbers

Representative references

  1. F. Bihelović, R. Matović, B. Vulović and R. N. Saičić: Organo-Catalyzed Cyclizations of pi-Allylpalladium Complexes: a New Method for the Construction of Five- and Six-Membered Rings, Organic Letters, 2007, 9, 5063.
  2. B. Vulović, F. Bihelović, R. Matović and R. N. Saičić: Organo-catalyzed Tsuji-Trost reaction: a new method for the closure of five- and six-membered rings, Tetrahedron 2009, 65, 10485.
  3. D. Velickovic, A. Dimitrijevic, F. Bihelovic, D. Bezbradica, R. Jankov, N. Milosavic: A higly efficient diastereoselective synthesis of a-isosalicin by maltase from Saccharomyces cerevisiae, Process Biochemistry, 2011, 46, 1698.
  4. A. Dimitrijevic, D. Velickovic, D. Bezbradic, F. Bihelovic, R. Jankov, N. Milosavic: Production of lipase from Pseudozyma aphidis and determination of the activity and stability of the crude lipase in polar organic solvents, Journal of the Serbian Chemical Society, 2011, 76, 1081.
  5. A. Dimitrijevic, D. Velickovic, F. Bihelovic, D. Bezbradica, R. Jankov, N. Milosavic: One-step, inexpensive high yield strategy for Candida antarctica lipase A isolation using hydroxyapatite, Bioresource Technology, 2012, 107, 358.
  6. F. Bihelovic, R. N. Saicic: Total Synthesis of (-)-atrop-Abyssomicin C, Angewandte Chemie International Edition, 2012, 51, 5687.
  7. Ratko Jankov, Dragica Šišović, Filip Bihelović, Slobodanka Antić: “HEMIJA” za prvi razred opšte gimnazije Zavod za udžbenike i nastavna sredstva PODGORICA, 2006.
  8. F. Bihelovic, I. Karadzic, R. Matovic, R. N. Saicic: Total synthesis and biological evaluation of (−)-atrop–abyssomicin C, Organic & Biomolecular Chemistrzy, 2013, 11, 5413.
  9. Z. Ferjancic, R. Matovic, F. Bihelovic: Diastereoselective addition of alkenylchromium(III) reagents to Garner’s aldehyde. Nozaki–Hiyama–Kishi coupling approach to sphingosines and ceramides, Journal of the Serbian Chemical Society, 2014, 79, 627.
  10. R. Matovic, F. Bihelovic, M. Gruden-Pavlovic, R. N. Saicic: Total synthesis and biological evaluation of atrop-O-benzyl-desmethylabyssomicin C, Organic & Biomolecular Chemistry, 2014, 12, 7682.
  11. D. Velickovic, N. Milosavic, D. Bezbradica, F. Bihelovic, A. Segal, D. Segan, J. Trbojevic, A. Dimitrijevic: The specificity of alpha-glucosidase from Saccharomyces cerevisiae differs depending on the type of reaction: hydrolysis versus transglucosylation, Applied Microbiology and Biotechnology, 2014, 98, 6317.
  12. L. Novkovic, M. Trmcic, M. Rodic, F. Bihelovic, M. Zlatar, R. Matovic, R. N. Saicic: Synthesis of endoperoxides by domino reactions of ketones and molecular oxygen, RSC Advances, 2015, 5, 99577.
  13. F. Bihelovic, Z. Ferjancic: Total Synthesis of (±)-Alstoscholarisine A, Angewandte Chemie International Edition 2016, 55, 2569. HIGHLIGHTED in SYNFACTS (2016, 12, 0330) and SYNFORM (2016, 5, A76).
  14. B. Vulovic, D. Kolarski, F. Bihelovic, R. Matovic, M. Gruden, R. N. Saicic: Gold(I)-Catalyzed Domino Cyclizations of Diynes for the Synthesis of Functionalized Cyclohexenone Derivatives. Total Synthesis of (-)-Gabosine H and (-)-6-epi-Gabosine H: Organic Letters 2016, 18, 3886.
  15. F. Bihelovic, B. Vulovic, R. N. Saicic: Synthesis of Natural Products and the Development of Synthetic Methodology: The Case Study of (–)-Atrop-abyssomicin C, Natural product communications 2017, 12, 1209-1214.
  16. F. Bihelovic, D. Stichnoth, F. Surup, R. Mueller, D. Trauner: A Synthesis of Crocagin A, Angewandte Chemistry International Edition, 2017, 56, 12848-12851.
  17. F. Bihelovic, B. Vulovic, R. N. Saicic: Gold(I)-Catalyzed C-O/C-C Bond-Forming Domino Reactions and Their Synthetic Applications, Israel Journal of Chemistry, 2018, 521-530.
  18. M. Trajkovic, Z. Ferjancic, R. N. Saicic, F. Bihelovic: Enantioselective Synthesis of the Platensimycin Core by Silver(I)‐Promoted Cyclization of D6‐a‐Iodoketone, Chemistry - A European Journal 2019, 25, 4340.
  19. M. Trajkovic, M. Pavlovic, F. Bihelovic, Z. Ferjancic, R. N. Saicic, Total Synthesis of (+)-Swainsonine, (–)-Swainsonine, (+)-8-epi-Swainsonine and (+)-Dideoxy-Imino-Lyxitol by an Organocatalyzed Aldolization/Reductive Amination Sequence, Natural Product Communication 2022, 17, doi:10.1177/1934578X221091672.
  20. Z. Ferjancic, A. Kukuruzar, F. Bihelovic: Total Synthesis of (+)-Alstonlarsine A, Angewandte Chemie International Edition 2022, 61, e202210297. HIGHLIGHTED in SYNFACTS (2022, 11, 1168).
  21. Z. Ferjancic, F. Bihelovic: Total Synthesis of (+)-Alstonlarsine A: Old Reactions in Modern Alkaloids Synthesis, Synlett 2023, 34, 203.
  22. F. Djurkovic, Z. Ferjancic, F. Bihelovic: Intramolecular Dearomative Inverse-Electron-Demand Diels Alder Strategy for the Total Synthesis of (+)-Alstonlarsine A, Journal of Organic Chemistry 2023, 88, 11618.
  23. Z. Ferjancic, F. Bihelovic, B. Vulovic, R. Matovic, M. Trmcic, A. Jankovic, M. Pavlovic, F. Djurkovic, R. Prodanovic, A. Dj. Djelmas, N. Kalicanin, M. Zlatovic, D. Sladic, T. Vallet, M. Vignuzzi, R. N. Saicic: Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies, Journal of Enzyme Inhibition and Medicinal Chemistry 2024, 39, 2289007.