Group Members (Faculty of Chemistry/ICTM)

  • Milan Nikolić, PhD - Associate Professor, University of Belgrade - Faculty of Chemistry
  • Simeon Minić, PhD - Assistant Professor/Senior Research Associate, University of Belgrade - Faculty of Chemistry
  • Srđan Stojanović, PhD - Principal Research Fellow, ICTM - Center for Chemistry
  • Nikola Gligorijević, PhD - Senior Research Associate, ICTM - Center for Chemistry
  • Lora Tubić - junior research assistant, PhD student in Biochemistry, University of Belgrade - Faculty of Chemistry
  • Ljubodrag Aleksić - junior research assistant, PhD student in Biochemistry, University of Belgrade - Faculty of Chemistry (PROMIS project)
  • Aleksandar Ivanov - junior research assistant, PhD student in Biochemistry, University of Belgrade - Faculty of Chemistry

Research Areas

  • Color stabilization of phycobilin proteins of cyanobacteria and red algae under high pressure or by binding small molecules (sugars, fatty acids, vitamins)
  • Bioactive and commercial potential of chromopeptides from cyanobacteria and red algae
  • Studies of the effects of phycobilin chromophores binding to blood proteins and DNA/RNA
  • effects of selected drugs (different classes of psychopharmaceuticals) on human blood proteins and erythrocytes
  • Bioinformatics analysis of the stability of selected proteins
  • Development of products based on bioactive compounds of cyanobacteria and algae as cell media components for meat cultivation
  • Development of hydrogels based on bioactive compounds of cyanobacteria and algae for use in the food industry

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Selected Publications

  • S. Minic, L. Velickovic, B. Annighöfer, A. Thureau, N. Gligorijevic, Z. Jovanovic, A. Brûlet, S. Combet. Probing the structural stability of R-phycocyanin under pressure. Protein Sci. 2024, 33(9), e5145. https://doi.org/10.1002/pro.5145
  • D. Jakovljević, M. Nikolić, V. Jovanović, T. Vidonja Uzelac, A. Nikolić-Kokić, E. Novaković, Č. Miljević, M. Milovanović, D. Blagojević. Influence of Long-Term Anti-Seizure Medications on Redox Parameters in Human Blood. Pharmaceuticals (Basel). 2024, 17(1):130. https://doi.org/10.3390/ph17010130
  • N. Sibinčić, M. Krstić Ristivojević, N. Gligorijević, L. Veličković, K. Ćulafić, Z. Jovanović, A. Ivanov, L. Tubić, C. Vialleix, T. Michel, T. Srdić Rajić, M. Nikolić, M. Stojadinović, S. Minić. Screening Algal and Cyanobacterial Extracts to Identify Potential Substitutes for Fetal Bovine Serum in Cellular Meat Cultivation. Foods. 2024, 13(23), 3741. https://doi.org/10.3390/foods13233741
  • L. Breberina, M.V. Zlatović, S.Đ. Stojanović, M.R. Nikolić. Amide-π Interactions in the Structural Stability of Proteins: Role in the Oligomeric Phycocyanins. Computation (Basel), 2024, 12(9), 172. https://doi.org/10.3390/computation12090172
  • Veličković L, Simović A, Gligorijević N, Thureau A, Obradović M, Vasović T, Sotiroudis G, Zoumpanioti M, Brulet A, Ćirkovic Veličković T, Combet S, Nikolić M, Minić S. Exploring and strengthening the potential of R-phycocyanin from Nori flakes as a food colourant. Food Chem. 2023;426:136669. https://doi.org/10.1016/j.foodchem.2023.136669
  • Šunderić M, Gligorijević N, Milčić M, Minić S, Nedić O, Nikolić M. Phycocyanobilin is a new binding partner of human alpha-2-macroglobulin that protects the protein against oxidative stress. J Biomol Struct Dyn. 2023;17:1-11. https://doi.org/10.1080/07391102.2023.2248273
  • Gligorijević N, Jovanović Z, Cvijetić I, Šunderić M, Veličković L, Katrlík J, Holazová A, Nikolić M, Minić S. Investigation of the Potential of Selected Food-Derived Antioxidants to Bind and Stabilise the Bioactive Blue Protein C-Phycocyanin from Cyanobacteria Spirulina. Int. J. Mol. Sci. 2023; 25(1):229. https://doi.org/10.3390/ijms25010229
  • Platanic Arizanovic L, Gligorijevic N, Cvijetic I, Mijatovic A, Ristivojevic MK, Minic S, Kokic AN, Miljevic C, Nikolic M. Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes? Int. J. Mol. Sci. 2023:24(10):8921. https://doi.org/10.3390/ijms24108921
  • A. Simović, S. Combet, T. Ćirković-Veličković, M. Nikolić, S. Minić. Probing the stability of the food colourant R-phycoerythrin from dried Nori flakes. Food Chem. 2022;374:131780. https://doi.org/10.1016/j.foodchem.2021.131780

Partners

Projects

Strengthening the potential of algal proteins for food colouring and fortification using high-pressure technology (PRESSION; No. ANSO-CR-PP-2021-01; 2022-2024/5)

A comprehensive platform for the selection and production of algae extracts for efficient serum-albumin replacement in meat farming (ALG2MEAT; American Good Food Institute project; 2023-2024/5)

Pep4Meat: Investigation of the potential of chromopeptides from algae as a substitute for serum components in meat farming (PROMIS 2023) (2024-2025)

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