Course code: 403B2 |
Course name: Regulation of Biochemical Processes |
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Academic year: |
2024/2025. |
Attendance requirements: |
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ECTS: |
4 |
Study level: |
basic academic studies |
Study program: |
Biochemistry: 4. year, winter semester, compulsory course |
Teacher: |
Milan R. Nikoliæ, Ph.D. |
Assistant: |
Simeon L. Miniæ, Ph.D. |
Hours of instruction: |
Weekly: two hours of lectures + one hour of exercises + one hour of labwork (2+1+1) |
Goals: |
This course will enable students to acquire basic and advanced knowledge of the mechanisms of biochemical regulation. |
Outcome: |
Students have mastered the essential biochemical regulatory mechanisms and basic laboratory techniques. |
Teaching methods: |
Lectures, theory exercises and experimental exercises. |
Extracurricular activities: |
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Coursebooks: |
Main coursebooks:
Supplementary coursebooks:
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Additional material: |
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Course activities and grading method |
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Lectures: |
10 points (2 hours a week) Syllabus: Course contents: General principles and concepts of the regulation of biochemical processes; homeostasis in the context of the thermodynamics of open systems;Structure, organization, and characteristics of signaling pathways: primary messengers, receptors, the coupling of receptors, second messengers, adaptor proteins and effector proteins; Signaling through G protein-coupled receptors;Phosphatidylinositol signaling system; Signaling through catalitic receptors;Signaling through nuclear receptors; Signaling coupled with ion-channel-coupled receptors;Gaseous signaling molecules; Integration pathways for signal transmission: vision and muscle contraction/relaxation;Signaling systems: signal integration, crosstalk mechanisms, and networks; Disruptions in signal transmission pathways; basics of redox signaling;Experimental approaches and methods in the cell signaling. |
Exercises: |
10 points (1 hour a week) Syllabus:
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Labwork: |
10 points (1 hour a week) Syllabus:
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Written exam: |
40 points |
Oral exam: |
30 points |