Course code:
202B2
Course name:
Organic Chemistry 2

Academic year:

2024/2025.

Attendance requirements:

201B2

ECTS:

10

Study level:

basic academic studies

Study program:

Biochemistry: 2. year, winter semester, compulsory course

Teachers:

Veselin R. Maslak, Ph.D.
full professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Aleksandra D. Mitrović, Ph.D.
assistant professor, Faculty of Chemistry, Studentski trg 12-16, Beograd

Assistants:

Vojislava E. Poštić
teaching assistant, Faculty of Chemistry, Studentski trg 12-16, Beograd

Katarina B. Komatović
teaching assistant, Faculty of Chemistry, Studentski trg 12-16, Beograd

Hours of instruction:

Weekly: five hours of lectures + one hour of exercises + four hours of labwork (5+1+4)

Goals:

This course continues to explore the concepts introduced in Organic Chemistry 1. The goal of this course is to help students learn about the properties and reactions of conjugated and aromatic systems, carbonyl and heterocyclic compounds, and of some complex organic compounds as well: carbohydrates, amino acids and proteins, nucleic acids and to master the synthesis of some natural and synthetic organic compounds.

Outcome:

Upon completing this course, students will be able to name complex organic compounds and understand the concept of aromaticity and complex mechanisms of organic reactions, particularly the Claisen, Dieckmann and Michael reactions. They will have gained a better understanding of the connection between the structure and reactivity of complex organic compounds and they will be able to plan and perform the synthesis of these compounds.

Teaching methods:

Lectures, experimental classes and practical classes.

Extracurricular activities:

Coursebooks:

  • P. Volhart, N. Šor: Organska hemija - struktura i funkcija, Data status, Nauka, Beograd
  • Ž. Čeković: Eksperimentalna organska hemija
  • Zorana Ferjančić, Filip Bihelović: Preparativna organska hemija, Univerzitet u Beogradu - Hemijski fakultet, SP Print, Beograd 2012. ISBN 978-86-7220-049-2
  • The teacher’s lecture notes and the presentations which accompany the lectures (in electronic form)

Additional material:

http://helix.chem.bg.ac.rs/~vmaslak/Organska_hemija_2-202B1/

  Course activities and grading method

Lectures:

0 points (5 hours a week)

Syllabus:

  1. Dienes: conjugated systems. Orbital symmetry.
  2. Aromatic compounds.
  3. Reactions of benzene and its derivatives.
  4. Phenols.
  5. The chemistry of naphthalene.
  6. Aldehydes and ketones.
  7. Carboxylic acids.
  8. Derivatives of carboxylic acids.
  9. Lipids. Steroids. Prostaglandins. Terpenes.
  10. Enolate ions, enols and α,β-unsaturated carbonyl compounds.
  11. Amines.
  12. Aromatic heterocycles.
  13. Amino acids, peptides and proteins, enzymes: biological catalysts.
  14. Carbohydrates.
  15. Nucleic acids.

Exercises:

0 points (1 hour a week)

Labwork:

15 points (4 hours a week)

Syllabus:

Students are expected to independently perform the synthesis of 6 (six) organic compounds (preparations) in one and/or more phases and by doing so they should use in practice the most important organic reactions and experimental techniques which they have mastered within the course Organic Chemistry 1. Apart from that, students should perform the synthesis of the derivatives of organic compounds and perform their characterization.

Colloquia:

30 points

Written exam:

55 points