[dr Mario V. Zlatovic]

Faculty of Chemistry, Studentski trg 12-16, Beograd
Department of Organic Chemistry

Phone:   011-2183460, 011-3336684

Phone (local):   684

Office:   482

Laboratory:   481

E-mail:   mario@chem.bg.ac.rs

Personal data

Born on April 7, 1963 in Šibenik, Croatia. Married. Speaks Serbian, English, Russian and Croatian language.

Education and qualifications

1981-1987: Undergraduate studies - Chemistry / Prirodno-matematički fakultet (Belgrade, Serbia)

1988-1996: Master of science studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2007: Doctoral academic (PhD) studies - Chemistry / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

History of employment

1988: Graduate assistant / Prirodno-matematički fakultet (Belgrade, Serbia)

1993: Graduate assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

1996: Teaching assistant / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2008-2010: Research associate / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2010-2021: Assistant professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2016-2023: Associate professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

2023: Full professor / University of Belgrade - Faculty of Chemistry (Belgrade, Serbia)

Scientific interest

My research interests are chemistry of natural products, especially those from marine origin, computer aided analysis of interactions of proteins with small molecules, CAMM/CADD, medicinal chemistry.

Other activities

Member of Serbian Chemical Society - Section for medicinal chemistry.

ChemNet Supervisor from October 8, 2020.

Member of the Committee for Exams Recognition from October 13, 2022 till February 7, 2024.

Member of the Board of the Faculty of Chemistry from June 22, 2023.

Member of the Committee for Exams Recognition from February 8, 2024.

From November 2009 till August 2010 worked as visiting scientist at National Cancer Institute, Fort Detrick, Frederick, Maryland, USA, under auspices of Fulbright foundation.

Educational activities

Participation in research projects

Finished projects:

  • 2011: The Synthesis of Aminoquinoline-based Antimalarials and Botulinum Neurotoxin A Inhibitors – 172008
    project type:   National Fundamental Research Projects
    project is funded by: Ministry of Science and Technological Development (Belgrade, Serbia)
  • 2011: – 172055
    project type:   National Fundamental Research Projects
    project is funded by: Ministry of Science and Technological Development (Belgrade, Serbia)
  • 2015: Small Molecule Antiviral Inhibitors – 1323839
    project type:   International
  • 2020: Small Molecule Anti-RNA-virus Therapy. Repurposing Iminosugars and Chloroquine Analogues Against COVID-19 (SMART Repurposing) – 7547552
    project type:   COVID-19
    project is funded by: Science Fund of the Republic of Serbia (Belgrade, Serbia)

Author identification numbers

Representative references

  1. Ribić, V.; Rečnik, A.; Komelj, M.; Kokalj, A.; Branković, Z.; Zlatović, M.; Branković, G. New Inversion Boundary Structure in Sb-Doped ZnO Predicted by DFT Calculations and Confirmed by Experimental HRTEM. Acta Materialia 2020, 199, 633–648. https://doi.org/10.1016/j.actamat.2020.08.035.
  2. Sović, I.; Cindrić, M.; Perin, N.; Boček, I.; Novaković, I.; Damjanović, A.; Stanojković, T.; Zlatović, M.; Hranjec, M.; Bertoša, B. Biological Potential of Novel Methoxy and Hydroxy Substituted Heteroaromatic Amides Designed as Promising Antioxidative Agents: Synthesis, 3D-QSAR Analysis, and Biological Activity. Chem. Res. Toxicol. 2019, 32 (9), 1880–1892. https://doi.org/10.1021/acs.chemrestox.9b00256.
  3. Breberina, L. M.; Zlatović, M. V.; Nikolić, M. R.; Stojanović, S. Đ. Computational Analysis of Non‐covalent Interactions in Phycocyanin Subunit Interfaces. Mol. Inf. 2019, 38 (11–12), 1800145. https://doi.org/10.1002/minf.201800145.
  4. Ribić, V. R.; Stojanović, S. Đ.; Zlatović, M. V. Anion–π Interactions in Active Centers of Superoxide Dismutases. International Journal of Biological Macromolecules 2018, 106, 559–568. https://doi.org/10.1016/j.ijbiomac.2017.08.050.
  5. Jevtić, I. I.; Grozdanić, N. D.; Šegan, S. B.; Zlatović, M. V.; Ivanović, M. D.; Stanojković, T. P. α-Glucosidase Inhibitory Activity and Cytotoxic Effects of Some Cyclic Urea and Carbamate Derivatives AU  - Popović-Djordjević, Jelena B. Journal of Enzyme Inhibition and Medicinal Chemistry 2017, 32 (1), 298–303. https://doi.org/10.1080/14756366.2016.1250754.
  6. Aleksić, I.; Šegan, S.; Andrić, F.; Zlatović, M.; Moric, I.; Opsenica, D. M.; Senerovic, L. Long-Chain 4-Aminoquinolines as Quorum Sensing Inhibitors in Serratia Marcescens and Pseudomonas Aeruginosa. ACS Chem. Biol. 2017, 12 (5), 1425–1434. https://doi.org/10.1021/acschembio.6b01149.
  7. Terzić, N.; Konstantinović, J.; Tot, M.; Burojević, J.; Djurković-Djaković, O.; Srbljanović, J.; Štajner, T.; Verbić, T.; Zlatović, M.; Machado, M.; Albuquerque, I. S.; Prudêncio, M.; Sciotti, R. J.; Pecic, S.; D’Alessandro, S.; Taramelli, D.; Šolaja, B. A. Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials? J. Med. Chem. 2016, 59 (1), 264–281. https://doi.org/10.1021/acs.jmedchem.5b01374.
  8. Borozan, S. Z.; Zlatović, M. V.; Stojanović, S. Đ. Anion-π Interactions in Complexes of Proteins and Halogen-Containing Amino Acids. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2016, 21 (3), 357—368. https://doi.org/10.1007/s00775-016-1346-y.
  9. Zlatović, M. V.; Borozan, S. Z.; Nikolić, M. R.; Stojanović, S. Đ. Anion–π Interactions in Protein–Porphyrin Complexes. RSC Adv. 2015, 5 (48), 38361–38372. https://doi.org/10.1039/C5RA03373J.
  10. Petrović, D.; Zlatović, M. Modeling Human Serum Albumin Tertiary Structure To Teach Upper-Division Chemistry Students Bioinformatics and Homology Modeling Basics. J. Chem. Educ. 2015, 92 (7), 1233–1237. https://doi.org/10.1021/ed500358f.
  11. Jovanović, M.; Gruden-Pavlović, M.; Zlatović, M. Stabilizing Non-Covalent Interactions of Ligand Aromatic Moieties and Proline in Ligand–Protein Systems. Monatshefte für Chemie - Chemical Monthly 2015, 146 (2), 389–397. https://doi.org/10.1007/s00706-014-1357-8.
  12. Videnović, M.; Opsenica, D. M.; Burnett, J. C.; Gomba, L.; Nuss, J. E.; Selaković, Ž.; Konstantinović, J.; Krstić, M.; Šegan, S.; Zlatović, M.; Sciotti, R. J.; Bavari, S.; Šolaja, B. A. Second Generation Steroidal 4-Aminoquinolines Are Potent, Dual-Target Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease and P. Falciparum Malaria. J. Med. Chem. 2014, 57 (10), 4134–4153. https://doi.org/10.1021/jm500033r.
  13. Reljic, Z.; Zlatovic, M.; Savic-Radojevic, A.; Pekmezovic, T.; Djukanovic, L.; Matic, M.; Pljesa-Ercegovac, M.; Mimic-Oka, J.; Opsenica, D.; Simic, T. Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and  In Silico Analysis. Toxins 2014, 6 (8). https://doi.org/10.3390/toxins6082348.
  14. Novaković, I.; Anđelković, U.; Zlatović, M.; Gašić, M. J.; Sladić, D. Bioconjugate of Lysozyme and the Antibacterial Marine Sesquiterpene Quinone Avarone and Its Derivatives. Bioconjugate Chem. 2012, 23 (1), 57–65. https://doi.org/10.1021/bc200330m.
  15. Zlatović, M. V.; Šukalović, V. V.; Roglić, G. M.; Kostić-Rajačić, S. V.; Andrić, D. B. The Influence of Dispersive Interactions on the Binding Affinities of Ligands with an Arylpiperazine Moiety to the Dopamine D2 Receptor. J. Serb. Chem. Soc. 2009, 74 (10), 1051–1061. https://doi.org/10.2298/JSC0910051Z.
  16. Šukalović, V. V.; Zlatović, M. V.; Roglic, G. M.; Kostić-Rajačić, S. V.; Andrić, D. B. Application of Hybrid Density Functional Trheory in Calculation of Edge-to-Face Interactions of Receptor-Ligand System. Acta Chimica Slovenica 2009, 56 (1), 270–277.
  17. Zlatovic, M. V.; Sukalovic, V. V.; Kostic-Rajacic, S. V.; Andric, D. B.; Roglic, G. M. Influence of N-1 Substituent Properties on Binding Affinities of Arylpiperazines to the Binding Site of 5-HT1A Receptor. J. Serb. Chem. Soc. 2006, 71 (11), 1125–1135. https://doi.org/10.2298/JSC0611125Z.
  18. Zlatović, M. V.; Sukalović, V. V.; Schneider, C.; Roglić, G. M. Interaction of Arylpiperazine Ligands with the Hydrophobic Part of the 5-HT1A Receptor Binding Site. Bioorganic & medicinal chemistry 2006, 14 (9), 2994—3001. https://doi.org/10.1016/j.bmc.2005.12.023.