Project type:   Training (international)

Grant agreement No.:   ANSO-TP-2022-06

Project is funded by:   ANSO (Kina, China)

Instituions where the research is conducted:

  • University of Belgrade - Faculty of Chemistry (Belgrade, Serbia) – Beneficiary
  • Karolinska bolnica i institut (Stokholm, Sweden) – Beneficiary
  • Medicinski fakultet u Hong Kongu (Hong Kong, China) – Beneficiary
  • Srebrnjak dečija bolnica (Zagreb, Croatia) – Beneficiary

Project realization is scheduled from January 1, 2023 till December 31, 2024.

Project staff

Principal investigator:   Marija M. Stojadinović, University of Belgrade - Faculty of Chemistry (Beograd, Serbia)

(click to display the full list of investigators)

Short description of the project

Allergy to house dust mite (HDM) is the main cause of persistent allergic rhinitis and asthma worldwide. In addition, crustacean seafood allergy is an important cause of food allergy and anaphylaxis in both Europe and Asia. It is suspected that some seafood allergens have similar structure to HDM allergens and can cause hypersensitivity. Tropomyosin from HDMs has a high sequence homology to shrimp tropomyosin, and cross-reactivity between them has been demonstrated. Therefore, it was postulated that the exposure to inhaled or immunotherapy supplemented tropomyosin from HDMs could be the primary sensitization route for seafood allergy. However, it has been reported only recently that the sensitization profiles to HDM allergens differ considerably among distinct geographic areas. We believe that beside tropomyosin other allergens from HDM and seafood need to be assessed for their sensitization potency and we intend on comparing the sensitization profiles in the European and Asian allergic cohorts. Data from this study would be novel and highly valuable for the diagnosis and treatment of HDM and seafood allergic patients worldwide.


To address the proposed scientific topic this project aims in forming a collaborative and a cooperation network between the research and clinical institutions from the ANSO member list and beyond it. Collaborators were chosen carefully to match each other’s expertise, so that the team can set up a research and exchange platform, which can successfully tackle on the major challenges in seafood and dust mite allergy diagnostic and management. To pursue the desired objectives of this project several short-term scientific exchanges will be organized to support researcher and resource mobility. This will strengthen the research, innovation and visibility of the partners towards the joint scientific goal.