Course code: 454B2 |
Course name: Mechanisms of Action of Physiologically Active Compounds |
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Academic year: |
2024/2025. |
Attendance requirements: |
There are no requirements. |
ECTS: |
4 |
Study level: |
graduate academic studies |
Study program: |
Biochemistry: 1. year, winter semester, elective (E53B2) course |
Teacher: |
Milan R. Nikoliæ, Ph.D. |
Assistant: |
Simeon L. Miniæ, Ph.D. |
Hours of instruction: |
Weekly: two hours of lectures + two hours of labwork (2+0+2) |
Goals: |
The course is based on prior knowledge of signaling pathways and metabolism regulation to understand their mutual connection and modulation capabilities of their functions by using drugs. The primary routes of administration, transport, distribution, and action of drugs (pharmacokinetics and pharmacodynamics) will be elaborated on the example of psychopharmacology, therapy of hyperlipidemia, hypertension, and diabetes, as well as chemotherapeutics. The final part of the course will briefly cover nanotechnologies and their applications in medicine. |
Outcome: |
Upon successful completion of the course, a student will be able to: independently and comprehensively considers the effects of biologically active substances (drugs), mechanisms of drug action, and strategy of drug transport in the target tissues. |
Teaching methods: |
Lectures, experimental exercises, and seminar paper. |
Extracurricular activities: |
— |
Coursebooks: |
Main coursebooks:
Supplementary coursebooks:
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Additional material: |
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Course activities and grading method |
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Lectures: |
10 points (2 hours a week) Syllabus:
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Labwork: |
20 points (2 hours a week) Syllabus: Pleiotropic effects of physiologically active substances: determining the antioxidant potential of selected classes of drugs and herb extracts; influence of drugs on the structure and activity of selected blood proteins.
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Semester papers: |
30 points |
Oral exam: |
40 points |